Mechanisms and Disease Pathogenesis Underlying Metal-Induced Oxidative Stress
نویسندگان
چکیده
منابع مشابه
Metal-Induced Oxidative Stress and Cellular Signaling Alteration in Animals
Contamination by heavy metals has attracted increasing attention considering the ability of these elements in producing serious consequence to ecosystem, and especially on animals health. Due to their widespread use in human activities such as industry, agriculture and even as medicine (e.g. arsenic, selenium and platinum), numerous health risks may be associated with exposure to these substanc...
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Diabetes markedly raises the risk of microvascular and macrovascular disease, the major contributors to higher morbidity and mortality in this increasingly prevalent disorder. Oxidative stress has been postulated as one major contributor to long-term diabetic complications. However, there is considerable controversy regarding the nature, magnitude, and mechanisms of oxidative stress in the diab...
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Hyperhomocysteinemia decreases vascular reactivity and is associated with cardiovascular morbidity and mortality. However, pathogenic mechanisms that increase oxidative stress by homocysteine (Hcy) are unsubstantiated. The aim of this study was to examine the molecular mechanism by which Hcy triggers oxidative stress and reduces bioavailability of nitric oxide (NO) in cardiac microvascular endo...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2018
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2018/7612172